Research progress of ferroptosis in the mechanism of cerebral ischemia reperfusion injury
Author:
Affiliation:

The First Affiliated Hospital of Kunming Medical University

Fund Project:

National Natural Science Foundation of China (No. 81960250); Key Project of Kunming Medical Joint Project of Yunnan Science and Technology Plan (No. : 202201AY070001-037)

  • Article
  • | |
  • Metrics
  • | | | | |
  • Comments
    Abstract:

    Ferroptosis is a newly cell death mode discovered in recent years, involving in a variety of pathophysiological processes, such as ischemia reperfusion injury, neurodegenerative diseases and tumors, etc. At present, there is a lack of effective methods to prevent and treat ischemic stroke worldwide, and ferroptosis which is involved in cerebral ischemia reperfusion injury. 50 articles were included in this paper after searching the related literature, which published in databases such as PebMed, Wanfang, CNKI and VIP in recent years. Discussing theIorn metabolism and the concept, mechanism and regulation of ferroptosis, the role of ferroptosis in the mechanism of cerebral ischemia reperfusion injury, and the methods of inhibiting ferroptosis, this paper attempts to provide reference for finding a new potential treatment for ischemic stroke from the direction of inhibiting ferroptosis.

    Reference
    Related
    Cited by
Get Citation
Share
Article Metrics
  • Abstract:263
  • PDF: 0
  • HTML: 0
  • Cited by: 0
History
  • Received:May 11,2023
  • Revised:March 26,2024
  • Adopted:April 12,2024
Article QR Code