Snake bite is a common clinical emergency, which has the characteristics of acute onset, rapid changes in condition, high disability and mortality rates. In addition to the common systemic and local tissue damage, snake envenomation can also cause significant complications, including immediate and delayed effects. These complications are also the main causes of disability and even death caused by snake bite, which seriously affect the long-term prognosis and quality of patients’ life. This paper summarizes the symptoms, diagnosis and treatment of snakebite complications from the aspects of blood system, nervous system, motor system, endocrine system, reproductive system and other aspects, in order to provide references for effective and precise treatment of snake bite in clinical practice.