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Research progress on the mechanism of miR-138-5p in osteoarthritis
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Affiliation:

1.Peking University Shenzhen Hospital;2.Shenzhen Second People'3.'4.s Hospital

Fund Project:

The National Natural Science Foundation of China (General Program, Key Program, Major Research Plan)

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    Abstract:

    MiR-138-5p, as a microRNA, plays an important regulatory role in the pathogenesis of osteoarthritis. It regulates various biological processes such as inflammation, cell apoptosis and proliferation, and matrix degradation in osteoarthritis by modulating signaling pathways including NF-κB, Wnt/β-catenin, and PI3K/AKT. This review summarizes the research progress on the mechanism of miR-138-5p on osteoarthritis.

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History
  • Received:November 28,2023
  • Revised:March 25,2024
  • Adopted:June 28,2024
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