Dioscin promotes apoptosis of HepG2 cell through inhibiting Wnt/β-catenin signaling pathway

Dioscin promotes apoptosis of HepG2 cell through inhibiting Wnt/β-catenin signaling pathway
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                        liangyuqiong1liangyuqiong
Faculty of Chinese Medicine Science Guangxi university of chinese medicine
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huangqing2huangqing
The First Affiliated Hospital of Guangxi University of Traditional Chinese medicine
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Affiliation:1.Faculty of Chinese Medicine Science Guangxi university of chinese medicine;2.The First Affiliated Hospital of Guangxi University of Traditional Chinese medicine
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Abstract:

Objective ?To detect the effects of apoptosis on HepG2 cell induce by Dioscin and its possible mechanism of anti-hepatocellular carcinoma. Methods The HepG2 human hepatocellular carcinoma cells were exposed with 0.25,0.5,1,2,4,6,8 μmol/L dioscin, and then the cell proliferation ability was measured with

Key words:dioscin; HepG2 cells;hepatocellular carcinoma; Wnt/β-catenin signaling pathway;apoptosis

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Received:March 01,2024
Revised:April 07,2024
Adopted:June 17,2024
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