Microglia efferocytosis is the process by which microglia phagocytose damaged and dead cells, with anti-inflammatory and pro-damage repair effects. Recent studies have shown that microglia efferocytosis plays a crucial role in the pathogenesis of Alzheimer"s disease (AD) and may be a novel therapeutic target for AD. This paper reviews the relationship between microglia efferocytosis and AD pathogenesis and the potential of efferocytosis-related molecules as therapeutic targets for AD. The aim is to provide new ideas and approaches for the treatment of AD.