Abstract:Throat reflux disease (LPRD) is a disease that occurs in both the upper respiratory tract and the upper digestive tract. The pathogenesis is complex and there is still a lack of effective treatment. Reasonable animal models and standard evaluation methods are particularly important to explore the pathogenesis and develop new therapeutic drugs. New Zealand rabbits are commonly used to model the disease, and balloon dilatation is commonly used to model the disease. The standard evaluation methods of this disease include symptom observation and evaluation, imaging evaluation and PH monitoring. The animal models and evaluation indexes of pharyngeal reflux were reviewed in detail by referring to domestic and foreign literatures, in order to provide reference for future research.