【】With the rapid development of biotechnology, researchers are constantly seeking new methods to improve the efficiency and accuracy of biomedical research and drug development, promoting interdisciplinary integration. The rapid advancement of artificial intelligence (AI) technologies has brought unprecedented opportunities to this field. By integrating various AI models, researchers can better utilize multi-omics data, identify disease phenotypes, simulate disease processes, interpret animal behavior, assess treatment effects, improve experimental design, reduce the use of experimental animals, enhance animal facility management, and improve animal welfare.