Cinnamomum cassia Presl belongs to the camphor family of evergreen tree plants, and its bark is used as medicine. It mainly contains volatile oil, polyphenols, polysaccharides, flavonoids, flavanols and other chemical constituents, which have the effects of inhibiting neuroinflammatory response, oxidative stress, neuronal apoptosis, neuroprotection as well as improving cerebral ?ischemia-reperfusion. With the progress of modern medicine, the drug is found to have unique advantages in the prevention and treatment of central nervous system diseases (CNSD), and cinnamon and its preparations have been widely used in the treatment of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, so cinnamon treatment of CNSD has become one of the hot research directions. At present, the mechanism of action of cinnamon in the nervous system has not been comprehensively outlined and summarised, therefore, this paper summarises the progress of experimental research on the treatment of CNSD with cinnamon at home and abroad in recent years by summarising the progress of experimental research on the treatment of CNSD, to provide evidence-based medical evidence for the clinical research and development of the use of cinnamon.