The effects of four different modeling methods on HPA axis, hemorheology, platelet aggregation rate and myocardial ischemia in rats.
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Affiliation:

1.Guangxi University of Traditional Chinese Medicine;2.Guangxi University of Chinese Medicine

Fund Project:

1. Guangxi University of Chinese Medicine, Nanning 530200 , China; 2 Guangxi Key Laboratory of Chinese Medicine Foundation Research, Guangxi University of Chinese Medicine,Nanning530200 , China; 3. Key Laboratory of Guangxi Characteristic Experimental Animal Disease Model, Nanning 530200, China

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    Abstract:

    Objective? To observe the effects of four different modeling methods on the hypothalamus ?pituitary ?adrenal (HPA) axis, blood rheology, platelet aggregation rate and myocardial ischemia in rats, and to provide new ideas for the establishment of a rat model of “double heart” disease that is more in line with clinical diagnosis and treatment characteristics. Methods ?Sixty-nine male SD rats were randomly divided into the normal group, the chronic unpredictable mild stimulation (CUMS) group, the isoproterenol (ISO) group, the high-fat diet(HF

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History
  • Received:February 09,2025
  • Revised:June 03,2025
  • Adopted:June 05,2025
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