Expression levels and targets of more than fifty miRNAs in glioma

doi:10.3969.j.issn.1671-7856.2016.07.014

Home > Archive>Volume 26, Issue 7, 2016 >79-84. DOI:10.3969.j.issn.1671-7856.2016.07.014

Expression levels and targets of more than fifty miRNAs in glioma
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                        10.3969.j.issn.1671-7856.2016.07.014
                    
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                        LIU Tai-qiLIU Tai-qi
Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang 524023, China
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CHEN Si-yuCHEN Si-yu
Guangdong Key Laboratory for Research and Development of Natural Drugs, Guangdong Medical College, Zhanjiang 524023, China
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LI Wen-deLI Wen-de
Key Laboratory of Guangdong Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou 510663
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HUANG RenHUANG Ren
Key Laboratory of Guangdong Laboratory Animals, Guangdong Laboratory Animals Monitoring Institute, Guangzhou 510663
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Abstract:

miRNAs are a class of small endogenous RNAs that degrade target mRNAs or repress their translation process. Several miRNAs in glioma are up-regulated, while some others down-regulated. Some miRNAs promote tumorigenesis; some others, however, play a similar function of tumor suppressor genes. Therefore, studies on the expression profiles of miRNAs in glioma may afford auxiliary basis for early clinical diagnosis and novel srtategies for therapy of glioma. This paper will review on researches about the expression levels of miRNAs and their targets in glioma.

Key words:Glioma;miRNA;Target

Reference

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