The outbreak of Corona Virus Disease 2019 brought great challenges to the allocation of health human resources in medical and health institutions. Not only should the hospitals undertake the medical treatment and on-site rescue of patients caused by emergencies, but also compact defenses to minimize the spread of virus in medical institutions, avoid cross infection, and take daily medical services into account. This study aims to summarize the hospital’ s human resources emergency management strategies in a comprehensive public hospital during Corona Virus Disease 2019, in order to provide reference for other hospitals to deal with public health emergencies.