Research progress of the microbiota-gut-brain axis and alcohol-induced brain injury
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1.College of Pharmacy, Dali University, Dali 671000, China. 2. College of Public Health, Dali University, Dali 671000. 3. Xiangtan Medicine and Health Vocational College, Xiangtan 411104. 4. Department of Agriculture and biological Science, Dali University, Dali 671000. 5. Yunnan Provincial Key Laboratory of Entomological Biopharmaceutical R&D, Dali University, Dali 671000

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R-33

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    Abstract:

    Alcohol can induce brain dysfunction, and gut microbiota can mediate the effects of alcohol on brain injury through the gut-brain axis. At present, the mechanisms of alcohol-mediated brain injury through the microbiota-gut- brain axis mainly include inflammation, endotoxins and tryptophan metabolism. Exploring the interactions between alcohol and the microbiota-gut-brain axis will be helpful for understanding the effects of alcohol on the brain, and will provide a new way to explore the pathogenesis of alcohol-induced brain injury.

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History
  • Received:November 06,2020
  • Revised:
  • Adopted:
  • Online: October 25,2021
  • Published: