Abstract:Rheumatoid arthritis ( RA) is a common autoimmune disease characterized by chronic synovial inflammation with joint cartilage and bone damage. Under Traditional Chinese Medicine, RA is categorized as a “ Bi disease.” Various RA models have been developed, including induced model, spontaneous genetic modification model, and model of Traditional Chinese Medicine syndrome. These models were reviewed and summarized in terms of their theoretical basis, typical characteristics, evaluation method , main usages, and degree of agreement. This paper also deals with the relationship between intestinal flora and RA to provide a reference for follow-up research.